Pharmacology Proctored ATI Practice Exam 2026 – Comprehensive Test Prep

After administering phenytoin IV, a nurse should plan to administer a saline solution. Phenytoin is an anti-seizure medication that can cause local irritation and potential tissue damage if it leaks from the vein. A saline solution helps to dilute the medication and reduce the risk of tissue injury. Administering an antacid, applying a cold compress, or monitoring for hypotension are not necessary or recommended after administering phenytoin IV. Administering an antacid would not prevent tissue damage from the medication, applying a cold compress would not address the potential tissue damage, and monitoring for hypotension is not associated with phenytoin administration. Therefore, administering a saline solution is the most appropriate action to take after administering phenytoin IV.